19 October 2009
A comparison of different treatment managements in patients with acute deep vein thrombosis by the effects on enhancing venous outflow in the lower limb
Ali RahmanABDEFG, Mehmet Cengiz ColakABEFG, Latif UstunelBDE, Mustafa KocBDE, Ercan KocakocEF, Cemil ColakCDMed Sci Monit 2009; 15(11): CR588-593 :: ID: 878244
Abstract
Background
This study aimed at evaluating the benefits of the traditional management of acute deep vein thrombosis (DVT), subcutaneous (sc) administration of low-molecular-weight heparin (LMWH) one dose a day and bed rest, and LMWH with compression stocking and early ambulation compared with LMWH with pneumatic compression (PC) in patients with DVT.
Material and Method
Forty-eight consecutive patients with DVT were separated evenly into four groups. Group A received intravenous unfractionated heparin, group B received sc injection of enoxaparin sodium and bed rest, group C received sc injection of enoxaparin sodium and thigh-length compression stockings, and group D received sc injection of enoxaparin sodium and PC for periods of up to 7 days.
Results
Comparing days 0 and 7, significant differences were determined in each group regarding differences in circumference of the two legs at the thigh and calf levels and the visual analogue scale (VAS) of pain, and in groups B, C, and D regarding the Lowenberg test for diseased and healthy legs (p<0.001). Between days 0 and 7, significant differences were found in the superficial femoral artery, superficial femoral vein, femoral vein, and the popliteal vein within groups A and D (p<0.05).
Conclusions
Traditional management, sc administration of low-molecular-weight heparin, and pneumatic compression of patients with DVT led to a faster reduction of leg swelling and pain and to increased volume flow through the deep veins of the legs.
Keywords: Systole - physiology, Pain Measurement, Leg - physiopathology, Veins - physiopathology, Arteries - physiopathology, Venous Thrombosis - therapy
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
06 Mar 2024 : Clinical Research
Comparison of Outcomes between Single-Level and Double-Level Corpectomy in Thoracolumbar Reconstruction: A ...Med Sci Monit In Press; DOI: 10.12659/MSM.943797
21 Mar 2024 : Meta-Analysis
Economic Evaluation of COVID-19 Screening Tests and Surveillance Strategies in Low-Income, Middle-Income, a...Med Sci Monit In Press; DOI: 10.12659/MSM.943863
10 Apr 2024 : Clinical Research
Predicting Acute Cardiovascular Complications in COVID-19: Insights from a Specialized Cardiac Referral Dep...Med Sci Monit In Press; DOI: 10.12659/MSM.942612
06 Mar 2024 : Clinical Research
Enhanced Surgical Outcomes of Popliteal Cyst Excision: A Retrospective Study Comparing Arthroscopic Debride...Med Sci Monit In Press; DOI: 10.12659/MSM.941102
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952