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04 August 2020: Database Analysis

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach

Shuang Song 12ABCDEF , Bin Li 12A , Zhen Jia 12C , Li Guo 12AG*

DOI: 10.12659/MSM.923547

Med Sci Monit 2020; 26:e923547

Figure 4 (A–L) ROC curve of the SIRT3 RNA levels for diagnosis of Alzheimer’s disease in 8 datasets. The gene symbol and GenBank accession ID on top of each ROC curve provide the subgroup information. The AUC, 95% CI of the AUC, OR, 95% CI of the OR and Wald test P value of SIRT3 RNA expression are shown under the curve. If the 95% CI of the AUC included 50%, further logistic regression would not proceed. ROC – receiver operating characteristic curve; AUC – area under the curve; CI – confidence interval; OR – odds ratio.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416