27 July 2020>: Laboratory Research
Biochemical Feature of LMO2 Interactome and LMO2 Function Prospect
Wenhao Wang 1BC* , Yaxin Chen 1BC* , Ying Chang 2AD* , Wei Sun 1EFG*DOI: 10.12659/MSMBR.924421
Med Sci Monit Basic Res 2020; 26:e924421
Figure 1 LMO2 has a wide spectrum of interaction members with several preferred domains and peptide features. (A) Pie plot showing the distribution of all positive LMO2-binding sequences from Y2H screening in each category. (B) The list of recurrently appeared domains and their relevant members in LMO2 core interactome. (C) The bubble plot showing the distribution of length, predicted secondary structure and stability of LMO2 binding peptides without any conserved domains in each category. Relative information was marked on the plot. (D) The bubble plot showing the distribution of predicted hydropathicity and isoelectric point (pI) of LMO2 binding peptides without any conserved domains. Relative information was marked on the plot. Y2H – yeast 2-hybrid; ORF – open reading frame; 3′-UTR – 3′-untranslated region; 5′-UTR – 5′-untranslated region; lncRNA – long non-coding RNA; NA – not available.