16 December 2020>: Laboratory Research
Paclitaxel Ameliorates Palmitate-Induced Injury in Mouse Podocytes
Seung Seob Son 1ABCDEF , Jeong Suk Kang 12CDEF , Eun Young Lee 123ACDEFG*DOI: 10.12659/MSMBR.928265
Med Sci Monit Basic Res 2020; 26:e928265
Figure 1 Effect of palmitate and paclitaxel on cell viability based on MTT assay. Cell viability was determined by MTT assay. (A) Mouse podocyte cells were incubated with 2 different concentrations of palmitate (300 μM and 400 μM) for 24 h. (B) Mouse podocyte cells were incubated with paclitaxel for 24 h at concentrations of 0–40 μM. IC50=22.7 μM. Error bars represent the mean±SEM (n=5). BSA – bovine serum albumin; PA – palmitate; PTX – paclitaxel. ** P<0.01 compared with control, *** P<0.001 compared with control.