Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

16 December 2020: Laboratory Research

Paclitaxel Ameliorates Palmitate-Induced Injury in Mouse Podocytes

Seung Seob Son 1ABCDEF , Jeong Suk Kang 12CDEF , Eun Young Lee 123ACDEFG*

DOI: 10.12659/MSMBR.928265

Med Sci Monit Basic Res 2020; 26:e928265

Figure 3 Effect of paclitaxel on palmitate-induced ER stress. Podocytes were treated with 300 μM palmitate with or without paclitaxel for 24 h. (A) Western blots (top) and densitometry (bottom) for ATF-6α and Bip. (B) Real-time PCR for CHOP, spliced XBP1, and Bip was normalized by β-actin mRNA level in the same sample. Error bars represent the mean±SEM. (n=3). BSA – bovine serum albumin; PA – palmitate; PTX – paclitaxel. * P<0.05, ** P<0.01, *** P<0.001 compared with palmitate.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416