Figure 6 Effect of paclitaxel on palmitate-induced apoptosis and fibrosis molecules. Podocytes were treated with 300 μM palmitate with or without paclitaxel for 18 h. (A) Western blot (top) and densitometry (bottom) for Bax, Caspase-3, and Bcl-2 demonstrating that palmitate-induced apoptosis was restored by paclitaxel. (B) Western blot (top) and densitometry (bottom) for fibronectin and TGF-β1, estimating that palmitate-induced apoptosis was restored by paclitaxel. Error bars represent the mean±SEM (n=3). BSA – bovine serum albumin; PA – palmitate; PTX – paclitaxel. *** P<0.001 compared with palmitate.