08 March 2023: Human Study
Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation
Chunlong Chen AEF , Qingzhen Liu CD , Hong Fan BD , Zhiyang Yu CF , Xueyan Leng B , Lidong Zhang ADF , Zhiqiang Zhou ADE*DOI: 10.12659/MSMBR.938849
Med Sci Monit Basic Res 2023; 29:e938849
Figure 1 The design of the study. TOF – train-of-four, measured by neuromuscular stimulator is composed of 4 equal stimuli delivered at intervals of 0.5 s. TOFR – train-of-four ratio, which is calculated by comparing the magnitude of the fourth twitch to the first one and indicates a non-depolarizing neuromuscular block, and a ratio ≥0.90 can be used as an objective measurement of neuromuscular reversal. PACU – Postanesthesia Care Unit. Strength measurements include spirometry and handgrip strength and ability to sit up unaided.