Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

01 October 2004

Laparoscopic detection of sentinel lymph nodes using blue dye in women with cervical and endometrial cancer

Zdenek Holub, AntonĂ­n Jabor, Jan Lukac, Lev Kliment

Med Sci Monit 2004; 10(10): CR587-591 :: ID: 11778

Abstract

Background:One of the cornerstones of gynecologic cancer surgery is the assessment and removal of the regional lymph nodes (LNs). Vital blue dye was used to shown the feasibility and accuracy of laparoscopic intraoperative lymphatic mapping of the sentinel lymph nodes (SNs) in patients with cervical and endometrial cancer (EC).Material/Methods: Thirty-two women were submitted to laparoscopic staging of cervical and endometrial cancer. Patent blue dye (BPD) was intraoperatively injected into the cervix in 6 cases with stage I and one case with stage II cervical cancer. In 25 cases of stage I EC, the BPD was intraoperatively injected into the cervix and uterine fundus. After the BPD procedure, the patients underwent pelvic lymphadenectomy or para-aortic lymph node dissection and either laparoscopically assisted vaginal hysterectomy (26 patients) or laparoscopic radical hysterectomy (5 patients).Results: Laparoscopically assisted surgical staging was successfully performed in all cases. SN detection was successful in 100% of 7 women with cervical cancer. In one patient with advanced cervical cancer the metastatic SN was found. A deposition of dye into at least one lymph node was found in 21 out of 25 cases (84%) in women with EC. Uptake of the BPD was observed in a total of 53 (14.4%) of 367 LNs. Histological analysis of two LNs of the 53 were positive for metastases, whereas the remaining 51 were negative.Conclusions: With the use of laparoscopy, accurate detection using blue dye on sentinel lymph nodes in uterine cancer is feasible technique.

Keywords: Endometrial Neoplasms - pathology, Endometrial Neoplasms - surgery, Color, Coloring Agents - analysis, Endometrial Neoplasms - surgery, Laparoscopy - methods, Lymphatic Metastasis - pathology, Sentinel Lymph Node Biopsy, Uterine Cervical Neoplasms - surgery

Comments

Most Viewed Current Articles

13 Apr 2020 : Original article  

Outcome of 24 Weeks of Combined Schroth and Pilates Exercises on Cobb Angle, Angle of Trunk Rotation, Chest...

DOI :10.12659/MSMBR.920449

Med Sci Monit Basic Res 2020; 26:e920449

11 May 2020 : Original article  

Analysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the ...

DOI :10.12659/MSMBR.924085

Med Sci Monit Basic Res 2020; 26:e924085

05 Jan 2021 : Review article  

A Southeast Asian Perspective on the COVID-19 Pandemic: Hemoglobin E (HbE)-Trait Confers Resistance Against...

DOI :10.12659/MSMBR.929207

Med Sci Monit Basic Res 2021; 27:e929207

10 Aug 2020 : Clinical Research  

Effects of Cognitive Task Training on Dynamic Balance and Gait of Patients with Stroke: A Preliminary Rando...

DOI :10.12659/MSMBR.925264

Med Sci Monit Basic Res 2020; 26:e925264

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416