Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

01 July 2005 : Extended abstract from EFAS 2011  

Effects of electrical stimulation on skin blood flow in controls and in andaround stage III and IV wounds in hairy and non hairy skin.

Jerrold Petrofsky, Ernie Schwab, Taiken Lo, Maria CĂșneo, James George, Jina Kim, Abdul Al-Malty

Med Sci Monit 2005; 11(7): CR309-316 :: ID: 16979

Abstract

Background: While wounds heal more quickly when electrical stimulation(ES) is applied, few studies have examined blood flow (BF) in and around wounds during ES in controlswith no wounds compared to wounds in diabetic and non diabetic subjects. Material/Methods: Ten subjectswith stage III and IV wounds and 8 controls were subjected to 5 minutes of biphasic ES (20 milliamps,pulse width 250 usec). Before, during, and after, BF were measured by a Laser Doppler Imager. Results:For the control subjects, in the fingers, BF increased from 307 flux to 687 after 5 min of ES to onefinger but BF also increased to other fingers indicating a reflex increase in flow mediated by the sympatheticnervous system. For hairy skin, there was a 12% increase in BF with ES and only in the line directlybetween the stimulating electrodes. For the patients (either with or without Type 2 diabetes), stimulationin the hand, leg and foot all caused a large increase in BF during and for 5 minutes after stimulation.In patients, BF was high in the wound area before ES and increased by 53% during, and remained high afterstimulation was over. Conclusions: The results show that in wounds, where BF is high due to bradykininand cytokine release, the vasoconstrictor tone is not present and electrical stimulation causes a largeincrease in circulation which lasts after stimulation is over.

Keywords: Diabetes Mellitus, Type 2 - complications, Diabetes Mellitus, Type 2 - complications, Electric Stimulation Therapy, Foot - blood supply, Hair, Hand - blood supply, Laser-Doppler Flowmetry, Regional Blood Flow, Skin - injuries, Wound Healing

0 Comments

Most Viewed Current Articles

13 Apr 2020 : Original article  

Outcome of 24 Weeks of Combined Schroth and Pilates Exercises on Cobb Angle, Angle of Trunk Rotation, Chest...

DOI :10.12659/MSMBR.920449

Med Sci Monit Basic Res 2020; 26:e920449

11 May 2020 : Original article  

Analysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the ...

DOI :10.12659/MSMBR.924085

Med Sci Monit Basic Res 2020; 26:e924085

05 Jan 2021 : Review article  

A Southeast Asian Perspective on the COVID-19 Pandemic: Hemoglobin E (HbE)-Trait Confers Resistance Against...

DOI :10.12659/MSMBR.929207

Med Sci Monit Basic Res 2021; 27:e929207

10 Aug 2020 : Clinical Research  

Effects of Cognitive Task Training on Dynamic Balance and Gait of Patients with Stroke: A Preliminary Rando...

DOI :10.12659/MSMBR.925264

Med Sci Monit Basic Res 2020; 26:e925264

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416