Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

Genetically determined coeliac disease in three family members.

D Miścicka-Sliwka, A Szaflarska-Szczepanik

Med Sci Monit 2000; 6(6): CS1182-1185 :: ID: 421204

Abstract

The work presents 3 members of a family of 4, who were diagnosed to havecoeliac disease (one classic and two latent forms of the disease). Genetic investigation regarding allthree patients revealed the existence of HLA DQ A1*0501 allele associated with susceptibility to coeliacdisease. Due to a much more frequent occurrence of atypical forms of coeliac disease in family members,than in general population, and due to risks resulting from tardy diagnoses and the lack of treatment,it is recommended that patients should be subjected to tests determining the presence of antiendomysialantibodies, as well as to genetic investigation with regards to latent coeliac disease.

Keywords: Adolescent, Alleles, celiac disease, Child, Gluten, HLA-DQ Antigens, Immunoglobulin A, Intestinal Mucosa, Pedigree

Comments

Most Viewed Current Articles

31 Dec 1969 : Original article  

Outcome of 24 Weeks of Combined Schroth and Pilates Exercises on Cobb Angle, Angle of Trunk Rotation, Chest...

DOI :10.12659/MSMBR.920449

Med Sci Monit Basic Res 2020; 26:e920449

31 Dec 1969 : Original article  

Analysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the ...

DOI :10.12659/MSMBR.924085

Med Sci Monit Basic Res 2020; 26:e924085

31 Dec 1969 : Review article  

A Southeast Asian Perspective on the COVID-19 Pandemic: Hemoglobin E (HbE)-Trait Confers Resistance Against...

DOI :10.12659/MSMBR.929207

Med Sci Monit Basic Res 2021; 27:e929207

31 Dec 1969 : Clinical Research  

Effects of Cognitive Task Training on Dynamic Balance and Gait of Patients with Stroke: A Preliminary Rando...

DOI :10.12659/MSMBR.925264

Med Sci Monit Basic Res 2020; 26:e925264

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416