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Impaired immunity against tetanus in Type 2 Diabetes.

Ali Tamer, Oguz Karabay, Hasan Ekerbicer, Mustafa Tahtaci, Belgin Selam, Harika Celebi

Med Sci Monit 2005; 11(12): CR580-584

ID: 438855

Available online: 2005-12-01

Published: 2005-12-01

Background: The aim of this study was to compare serum levels of tetanusantibody in diabetic patients over 50 years of age with those of age- and sex-matched non-diabetic controls.Material/Methods: The study population consisted of 115 type 2 diabetic patients and 115 age- and sex-matchednon-diabetic patients. Serum levels of tetanus IgG were measured by a commercial ELISA kit, and levelsover 0.1 IU/ml were considered protective. Results: Mean serum levels of tetanus antibody in the diabeticand control groups were 0.164+/-0.140 IU/ml vs. 0.374+/-0.534 IU/ml, respectively (p

Keywords: Aged, 80 and over, Antibodies, Bacterial - blood, Clostridium tetani - immunology, Diabetes Mellitus, Type 2 - immunology, Tetanus - immunology