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Apoptotic cell death in renal diseases. A new opportunities to better understanding of renal disease processes

Małgorzata Wągrowska-Danilewicz, Marian Danilewicz

Med Sci Monit 1996; 2(6): RA860-863

ID: 500509

Available online: 1996-11-01

Published: 1996-11-01

On the basis of the literature data the problem of apoptotic cell death in renal diseases is discussed. It is clear that programmed cell death via apoptosis plays an important role in renal disease. In particular it appears that apoptosis may have beneficial effects, by promoting removal of infiltrating leukocytes and 'unwanted' intrinsic cells. The study of programmed cell death in kidney may provide new experimental approaches to unravelling the pathogenesis of persistent inflammation and scarring. Since apoptosis can be regulated by external stimuli there is a prospect that this process might be regulated for therapeutic effect

Keywords: Apoptosis, programmed cell death, renal diseases