01 November 1999
Concentration of selected cytokines of gastric mucosa in children with Helicobacter pylori infectionElżbieta Maciorkowska, Maciej Kaczmarski, Andrzej Kemona
Med Sci Monit 1999; 5(6): CR1140-1145 :: ID: 503165
The concentrations of cytokines in homogenates of gastric mucosa were determined with ELISA and human antibodies (Endogen, USA) in 51 children complaining of abdominal pains. Morphological and histopathological assessment of gastric mucosa was performed in accordance with Sydney System in all the patients. The concentration of TNF-α, IL-2, IL-8 in gastric mucosa homogenates was statistically significantly higher than in control group. There were no statistically significant differences as to the concentration of IL-4 in mucosa. The concentration of IFN-γ in the studied group was statistically lower than in control subjects. High level of TFN-α, IL-2 and IL-8 in gastric mucosa homogenates infected with H. pylori in relation to children from control group might suggest that these cytokines play an important role in the pathogenesis of H. pylori infection.
Keywords: gastrointestinal mucosa, Cytokines, Helicobacter pylori
Most Viewed Current Articles
13 Apr 2020 : Original articleOutcome of 24 Weeks of Combined Schroth and Pilates Exercises on Cobb Angle, Angle of Trunk Rotation, Chest...
Med Sci Monit Basic Res 2020; 26:e920449
11 May 2020 : Original articleAnalysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the ...
Med Sci Monit Basic Res 2020; 26:e924085
05 Jan 2021 : Review articleA Southeast Asian Perspective on the COVID-19 Pandemic: Hemoglobin E (HbE)-Trait Confers Resistance Against...
Med Sci Monit Basic Res 2021; 27:e929207
10 Aug 2020 : Clinical ResearchEffects of Cognitive Task Training on Dynamic Balance and Gait of Patients with Stroke: A Preliminary Rando...
Med Sci Monit Basic Res 2020; 26:e925264