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Creutzfeld-Jakob disease (CJD) as an example of prion disease: New variant of CJD

Beata Sierzputowska-Lebensztejn, Dariusz Marek Lebensztejn, Maria Sobaniec-Łotowska

Med Sci Monit 1999; 5(6): RA1280-1285

ID: 503247

Available online: 1999-11-01

Published: 1999-11-01

Spongiform encephalopathies are the group of neurodegenerative infectious diseases recognised in humans and animals. One of these - Creutzfeld-Jakob disease (CJD) is caused by unconventional infectious factors defined as a prion proteins, infectious protein molecules devoid of nucleic acid. In recent years epidemic of bovine spongiform encephalopathy, reported in UK created fear against bovine-human transmission of the disease. First described causes of human encephalopathy, probably due to the bovine-human transmission of bovine spongiform encephalopathy was defined as a new variant of the Creutzfeld-Jakob disease (nvCJD). Our research presents chosen matters according to the prion diseases with taking into consideration the Creutzfeld-Jakob disease and its new variant (nvCJD).

Keywords: the Creutzfeld-Jakob disease (CJD), the Creutzfeld-Jakob disease new variant (nvCJD)