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Time for new indications for statins?

Maciej Banach, Dimitri P. Mikhailidis, Sverre E. Kjeldsen, Jacek Rysz

Med Sci Monit 2009; 15(12): MS1-5

ID: 878258

Available online: 2009-12-01

Published: 2009-12-01

The role of statins in the treatment and prevention of cardiovascular diseases, such as coronary artery disease, acute coronary syndromes, diabetes or stroke is well established. However, there are still some questions regarding the role of statins in patients with heart failure, hypertension, atrial fibrillation and chronic kidney disease (CKD). This editorial review discusses the current evidence regarding the use of statins in patients with hypertension (with or without dyslipidemia) or CKD. We need new large randomized clinical trials to confirm the potentially beneficial positive results obtained so far.

Keywords: Kidney Failure, Chronic - drug therapy, Hypertension - physiopathology, Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use, Cholesterol - blood, Cardiovascular Diseases - prevention & control, Blood Pressure - drug effects, Lipoproteins, LDL - blood