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21 December 2009

Coagulation changes in a siamese twin in SIRS after death of the other twin: a case study

Marcin OwczarekABCDEFG, Roman KazmirczukABDG, Andrzej ProkuratAF, Malgorzata ChrupekAF, Kamila Sadaj-OwczarekABEFG, Krzysztof KuszaACDEG

Med Sci Monit 2010; 16(1): CS1-5 :: ID: 878297

Abstract

Background
Conjoined twins represent a rare case of embryonic failure. Siamese twins' final outcome is usually associated with poor prognosis due to complications, among which the inflammatory and septic disturbances are often present.
Material and Method
The article describes Siamese twins of craniopagus type. One of the twins died of heart and aortic failure after 48 hours of life. The decision regarding surgical separation then became an emergency. At the same time laboratory results for the surviving twin I indicated steadily worsening coagulation functions and processes, which we believed were caused by the death of twin II, as well as by systemic inflammatory response syndrome (SIRS).
Results

Conclusions
Due to vascular conjunction between the twins' brains' circulatory systems the sequenced progress of coagulopathy was noticed in the surviving twin.

Keywords: Twins, Conjoined - surgery, Systemic Inflammatory Response Syndrome - complications, Dobutamine - therapeutic use, Blood Coagulation Disorders - etiology, Blood Chemical Analysis

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416