Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

01 August 2010

Ischemic post-conditioning: A feasible preventive method for cerebral hyperperfusion syndrome secondary to revascularization

Pengfei GeAE, Ping ZhangBC, Haifeng WangCD, Yanping ZhongDF, Yinan LuoG

Med Sci Monit 2010; 16(8): SC9-11 :: ID: 881084

Abstract

Cerebral hyperperfusion syndrome is a serious complication of revascularization after carotid endarterectomy, extracranial-intracranial bypass surgery, or stent placement. The mechanisms underlying cerebral hyper-perfusion syndrome are mainly ascribed to the dysfunction of cerebral auto-regulation to blood flow and injury of the endothelia in blood vessels. Although blood pressure control is often used to prevent cerebral hyper-perfusion after revascularization, cases of cerebral hyperperfusion are still reported in the literature. Current animal studies have shown that ischemic post-conditioning has protective effects on brain tissue, and further studies also showed that it had positive effects on human brachial artery and heart. Therefore, we propose the hypothesis that ischemic post-conditioning could be used to prevent cerebral hyperperfusion syndrome following revascularization. Although the mechanism of ischemic post-conditioning and its clinical application should be further investigated, it has shown its potential effectiveness as a feasible method for prevention of cerebral hyperperfusion syndrome.

Keywords: Neovascularization, Pathologic - prevention & control, Feasibility Studies, Endarterectomy, Carotid - adverse effects, Cerebrovascular Circulation - physiology, Brain Ischemia - physiopathology, Syndrome, Vascular Surgical Procedures - methods

0 Comments

Most Viewed Current Articles

13 Apr 2020 : Original article  

Outcome of 24 Weeks of Combined Schroth and Pilates Exercises on Cobb Angle, Angle of Trunk Rotation, Chest...

DOI :10.12659/MSMBR.920449

Med Sci Monit Basic Res 2020; 26:e920449

11 May 2020 : Original article  

Analysis of Psychological and Sleep Status and Exercise Rehabilitation of Front-Line Clinical Staff in the ...

DOI :10.12659/MSMBR.924085

Med Sci Monit Basic Res 2020; 26:e924085

05 Jan 2021 : Review article  

A Southeast Asian Perspective on the COVID-19 Pandemic: Hemoglobin E (HbE)-Trait Confers Resistance Against...

DOI :10.12659/MSMBR.929207

Med Sci Monit Basic Res 2021; 27:e929207

10 Aug 2020 : Clinical Research  

Effects of Cognitive Task Training on Dynamic Balance and Gait of Patients with Stroke: A Preliminary Rando...

DOI :10.12659/MSMBR.925264

Med Sci Monit Basic Res 2020; 26:e925264

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416