Abstract

ABSTRACT: Background: To understand the heterogeneity of platelets, we investigated the correlation between von Willebrand factor (vWf) and mean platelet volume (MPV) in subjects with isolated impaired fasting glucose (IFG). Material/Methods: We selected 48 subjects with isolated IFG and 48 normoglycemic control subjects matched for age, sex, and body mass index. We measured levels of vWf and MPV in all subjects. Results: The levels of vWf and MPV were significantly higher in the isolated IFG group than the control group (p<0.05) Also, vWf level was positively correlated with MPV level in subjects in the isolated IFG group (r=0.452, p=0.001). Conclusions: Our results suggest that vWf seems to be profoundly related to platelet volume in subjects with isolated IFG.

Keywords: Fasting - blood, Cell Size, Blood Platelets - cytology, Blood Glucose - metabolism, von Willebrand Factor - metabolism