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14 January 2013

Does pretreatment of bone marrow mesenchymal stem cells with 5-azacytidine or double intravenous infusion improve their therapeutic potential for dilated cardiomyopathy?

Sirui YangBCF, Jinhua PiaoDE, Lianhua JinDE, Yan ZhouACG

DOI: 10.12659/MSMBR.883737

Med Sci Monit Basic Res 2013; 19:20-31

Abstract

BACKGROUND: 0

MATERIAL AND METHODS: 0

RESULTS: 0

CONCLUSIONS: 0

Keywords: Myocardium - pathology, Natriuretic Peptide, Brain - blood, Mesenchymal Stem Cell Transplantation, Mesenchymal Stromal Cells - metabolism, Infusions, Intravenous, Heart Function Tests, Gene Expression Regulation - drug effects, Fibrosis, Collagen - metabolism, Cell Transdifferentiation - drug effects, Cardiomyopathy, Dilated - therapy, Bromodeoxyuridine - metabolism, Bone Marrow Cells - metabolism, Body Weight - drug effects, Azacitidine - pharmacology, RNA, Messenger - metabolism, Rats, Wistar, Troponin T - metabolism, Vascular Endothelial Growth Factor A - metabolism

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416