Rong Chen, Linong Ji, Liming Chen, Li Chen, Dehong Cai, Bo Feng, Hongyu Kuang, Hong Li, Yiming Li, Jing Liu, Zhongyan Shan, Zilin Sun, Haoming Tian, Zhangrong Xu, Yancheng Xu, Yuzhi Yang, Liyong Yang, Xuefeng Yu, Dalong Zhu, Dajin Zou
Department of Endocrinology, Changhai Hospital of Second Military Medical University of Chinese PLA, Shanghai, China (mainland)
Med Sci Monit 2015; 21:1440-1446
Type 2 diabetes mellitus (T2DM)-associated mortality and morbidity are strongly dependent on glycemic control. With T2DM prevalence increasing in China, we aimed to assess glycemic control rates in Chinese T2DM outpatients.
Material and Methods: A total of 9065 adult T2DM outpatients (5035 men) were assessed in 26 Chinese medical centers between August 2010 and April 2012. Patients were stratified according to BMI (kg/m2): <24, 24–28, and >28. Successful glycemic control was defined as glycated hemoglobin A1c (HbA1c) ≤7% or fasting plasma glucose (FPG) <7.0 mmol/L.
Results: Among the participants included in this study, 2939 had BMI <24, 3361 had BMI of 24–28, and 2764 had BMI >28. The glycemic control rate was only 32.6%, and the triple control rate for glycemia, blood pressure, and lipidemia was only 11.2%. Glycemic control rates by BMI group were 33.7% (<24), 33.8% (24–28), and 30.2% (>28) (p=0.005), and corresponding incidences of cardiovascular diseases (CVD) were 12.2%, 15.7%, and 15.9% (p<0.001). Multivariate logistic regression analysis demonstrated that older age (p<0.001), higher BMI (p=0.026), larger waist circumference (p<0.001), less education (p<0.001), and recent diagnosis (p<0.001) were independent risk factors for poor glycemic control.
Conclusions: The T2DM glycemic control rate in China is currently low, especially in older obese patients with poor education and recent diagnosis.
Keywords: Age Factors, Adult, Anthropometry, Blood Glucose - analysis, Body Mass Index, Cardiovascular Diseases - epidemiology, China - epidemiology, Comorbidity, Diabetes Complications - epidemiology, Diabetes Mellitus, Type 2 - epidemiology, Drug Monitoring, Educational Status, Hemoglobin A, Glycosylated - analysis, Lipids - blood, Outpatients - statistics & numerical data, Smoking - epidemiology