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Brainstem Auditory Evoked Potential in HIV-Positive Adults

Carla Gentile Matas, Alessandra Giannella Samelli, Rosanna Giaffredo Angrisani, Fernanda Cristina Leite Magliaro, Aluísio C. Segurado

Department of Physical Therapy, Speech-language Pathology and Audiology, and Occupational Therapy, School of Medicine (FMUSP), University of São Paulo, São Paulo, SP, Brazil

Med Sci Monit 2015; 21:3172-3178

DOI: 10.12659/MSM.894958

Available online:

Published: 2015-10-20


BACKGROUND: To characterize the findings of brainstem auditory evoked potential in HIV-positive individuals exposed and not exposed to antiretroviral treatment.
MATERIAL AND METHODS: This research was a cross-sectional, observational, and descriptive study. Forty-five HIV-positive individuals (18 not exposed and 27 exposed to the antiretroviral treatment – research groups I and II, respectively – and 30 control group individuals) were assessed through brainstem auditory evoked potential.
RESULTS: There were no significant between-group differences regarding wave latencies. A higher percentage of altered brainstem auditory evoked potential was observed in the HIV-positive groups when compared to the control group. The most common alteration was in the low brainstem.
CONCLUSIONS: HIV-positive individuals have a higher percentage of altered brainstem auditory evoked potential that suggests central auditory pathway impairment when compared to HIV-negative individuals. There was no significant difference between individuals exposed and not exposed to antiretroviral treatment.

Keywords: Anti-Retroviral Agents - therapeutic use, Adult, Audiometry, Pure-Tone, Brain Stem - pathology, Cross-Sectional Studies, Evoked Potentials, Auditory, Brain Stem - physiology, HIV Infections - physiopathology, HIV Seropositivity, Probability, young adult



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