Yıldıray Yıldırım, Abdullah Kaya, Taner Kar, Tuba Muftuoglu, Ali Ayata
Department of Ophthalmology, GATA Haydarpasa Training Hospital, Istanbul, Turkey
Med Sci Monit 2015; 21:3275-3278
The aim of this study was to determine prolidase activity in conjunctival tissue and its relationship with pterygium.
MATERIAL AND METHODS: Prolidase activity was measured in 23 pterygium and 25 healthy conjunctival tissues and the 2 groups were compared.
RESULTS: Prolidase enzyme activity could not be measured in either the healthy conjunctival or in pterygium tissues. The mean serum prolidase levels of the control and pterygium groups were 967.46±353.64 and 858.29±301.83, respectively. Statistically, there was no significant difference between the groups with regard to serum prolidase levels (p>0.05).
CONCLUSIONS: In conclusion, absence of prolidase activity in pterygium tissue indicates that there is no collagen turnover in this tissue. We may explain this finding with the elastin-rich structure of the conjunctiva.
Keywords: Adult, Case-Control Studies, Collagen - chemistry, Conjunctiva - pathology, Dipeptidases - metabolism, Elastin - chemistry, Gene Expression Regulation, Enzymologic, Pterygium - enzymology