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07 September 2015 : Review article  

Past and Present of Total Artificial Heart Therapy: A Success Story

Mostafa SamakABCDEF, Javid FatullayevABCDEF, Anton SabashnikovABCDEF, Mohamed ZeriouhABCDEF, Parwis B. RahmanianBCDE, Yeong-Hoon ChoiBCDE, Jens WippermannBCDE, Thorsten WahlersBCDE, Bastian SchmackBCDE, Arjang RuhparwarBCDE, Pascal M. DohmenBCDEF, Matthias KarckBCDE, Aron-Frederik PopovABCDEF, André R. SimonABCDEF, Alexander WeymannABCDEFG

DOI: 10.12659/MSMBR.895418

Med Sci Monit Basic Res 2015; 21:183-190

Abstract

ABSTRACT: The totally artificial heart (TAH) is among the most prominent medical innovations of the 21st century, especially due to the increasing population with end-stage heart failure. The progressive course of the disease, its resistance to conventional therapy, and the scarcity of hearts available for transplantation were the prime impetus for developing a TAH, especially when other options of mechanical circulatory assist devices are exhausted. In this review, we narrate the history of TAH, give an overview of its technology, and address the pros and cons of the currently available TAH models in light of published clinical experience.

Keywords: Heart Transplantation - trends, Heart Diseases - therapy, Heart, Artificial - trends, Prosthesis Design

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416