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Symptomatology Patterns in Children with Allergic Rhinitis

Michael Katotomichelakis, Theodoros Iliou, Ioannis Karvelis, Evangelos Giotakis, Gerasimos Daniilides, Eleni Erkotidou, Christos Lazaridis, George K. Anastassopoulos

Department of Otorhinolaryngology, Medical School, Democritus University of Thrace, Alexandroupolis, Evros, Greece

Med Sci Monit 2017; 23:4939-4946

DOI: 10.12659/MSM.903136

Available online:

Published: 2017-10-16

BACKGROUND: Although allergic rhinitis (AR) is recognized as a growing global health disease with considerable importance for patients’ lives, especially among children and adolescents, there is a lack of population studies concerning symptomatology patterns of the disease. The present study aimed to explore symptoms prevalence among school-aged children, to detect any correlation between allergen sensitivities with symptomatology patterns, and, finally, to evaluate the association of the sensitivity grade score with symptoms severity or seasonality.
MATERIAL AND METHODS: This was a cross-sectional, observational study in a childhood population. The first stage included recruitment of children and parental-completed questionnaires. The second stage included skin-prick tests for the most common allergens. Severity of symptoms was self-evaluated using a scale that ranged from “0” (no symptoms), “1” (mild), and “2” (moderate-to-severe). AR was classified as seasonal (SAR) or perennial (PAR).
RESULTS: The most frequent symptoms were reported for nasal obstruction, sneezing, and rhinorrhea. All nasal symptoms were significantly more profound among children with HDM sensitivity. However, more symptoms, not only nasal, but also ocular and general ones, were detected among patients with grass pollen sensitivity. Patients with PAR reported more severe symptoms. SAR was associated with mild disease. Finally, the sensitivity grade score was significantly correlated with symptom severity.
CONCLUSIONS: Our results suggest that allergen sensitivity may be correlated with symptomatology patterns among children who have allergic rhinitis.

Keywords: Adolescent, Rhinitis, Allergic, Seasonal, Signs and Symptoms, Skin Tests