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13 May 2019 : Review article  

Recent Advances in the Surgical Treatment of Advanced Gastric Cancer: A Review

Zhaoyang Tan1AEF*

DOI: 10.12659/MSM.916475

Med Sci Monit 2019; 25:3537-3541

Abstract

ABSTRACT: Gastric cancer is a common malignancy with a poor prognosis, and surgical treatment remains the first-line approach to treatment to provide a cure. Despite advances in surgical techniques, radiotherapy, chemotherapy, and neoadjuvant therapy, gastric cancer remains the second leading cause of cancer death worldwide. Although the 5-year survival rate of early gastric cancer can reach >90%, due to the low early diagnosis rate, most patients present with advanced-stage gastric cancer. Therefore, there has been increasing interest in improving surgical treatment of advanced gastric cancer. Lymph node dissection is an important part of the surgical treatment of advanced gastric cancer due to the high incidence of lymph node metastasis. Although prospective studies have confirmed the safety and feasibility of laparoscopic surgery for early gastric cancer, the relevant treatment models of advanced gastric cancer still need to be further explored and validated. This review aims to provide an update on the recent advances in the surgical treatment of advanced gastric cancer.

Keywords: Laparoscopes, Lymph Node Excision, Stomach Neoplasms, Early Detection of Cancer, Gastrectomy, Laparoscopy, Lymphatic Metastasis, Neoadjuvant Therapy, Stomach, Survival Rate

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416