Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

20 May 2010

Comparison of efficacy of MR sequences used for detection of focal liver lesions

Andrzej Cieszanowski, Agnieszka Grodzicka, Edyta Maj, Barbara Gornicka, Kaczynski Bartosz, Mariusz Grodzicki, Marek Krawczyk, Olgierd Rowinski

Med Sci Monit 2010; 16(1): 66-74 :: ID: 880586

Abstract

Background: The purpose of this study was to compare the sensitivities of different MR sequences (T2 TSE, DW EPI, T1 SGE) in detection of focal hepatic lesions.
Material/Methods: Evaluation included the MR studies (1.5T Unit: Magnetom Avanto) of 81 patients. Pathologic verification was obtained in 29 patients, whereas in remaining 52 patients, final diagnosis was based on other imaging studies, follow-up, and clinical data. In 56 patients, 171 liver lesions were confirmed: 84 malignant (52 metastases, 20 HCCs, 9 hemangioendotheliomas, 2 CCAs, 1 cystadenocarcinoma), and 87 benign (35 cysts, 31 hemangiomas, 13 abscesses, 7 FNHs, 1 cystadenoma). In 25 patients, liver lesions were excluded. Two radiologists identified the number of lesions on images obtained with the use of following sequences: T2WTSE, T2W fat-sat TSE, DW EPI (b=50,400,800 s/mm2), chemical shift T1 SGE (In-Out SGE), 3D T1 spoiled gradient-echo 3DT1SGE, dynamic 3DT1SGE post-Gd-BOPTA injection (with arterial, portal venous, parenchymal, 5 min-delayed phases) and 3DT1SGE 60-90 min post-Gd-BOPTA.
Results: Applied MR techniques yielded following sensitivities for detection of focal hepatic lesions: T2TSE 78.9%, T2 fat-sat 89.5%, DW EPI 95.9%, chemical shift T1SGE 80.7%, 3DT1SGE 81.9%, 3DT1SGE in arterial phase 93.0%, in portal venous phase 92.4%, in parenchymal phase 87.7%, in delayed phase 87.1%, and in hepatobiliary phase (60–90 min post-Gd-BOPTA) 84.8%.
Conclusions: The highest number of focal hepatic lesions was visualized on DW EPI sequence (n=164, sensitivity – 95.9%), followed by 3DT1SGE in arterial phase (n=159, sensitivity – 93.0%), 3DT1SGE in portal venous phase (n=158, sensitivity – 92.4%), and T2TSE fat-sat sequence (n=153, sensitivity – 89.5%).

Keywords: Magnetic Resonance Imaging, Liver Neoplasms, Contrast Media, Gadobenate dimeglumine

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750