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04 August 2020: Database Analysis

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach

Shuang Song 12ABCDEF , Bin Li 12A , Zhen Jia 12C , Li Guo 12AG*

DOI: 10.12659/MSM.923547

Med Sci Monit 2020; 26:e923547

Table 1 Demographic features of 8 RNA expression datasets from microarray analyses of Alzheimer’s disease brain tissues included in the study.

GEO IDTissueCase groupControl groupCountryPlatform
Total sampleFemale %Age (years)Total sampleFemale %Age (years)
MedianMaxMinMedianMaxMin
GSE15222Mixed cortex17650.0083.65102.36818745.458210065USAGPL2700
GSE33000Prefrontal cortex31056.45821005315721.666222106USAGPL4372
GSE132903Middle temporal gyrus9749.488698709848.988510270USAGPL10558
GSE48350Mixed cortex8058.7586956017347.40699920USAGPL570
GSE44771Visual cortex12951.94821005510118.816110622USAGPL4372
GSE44770Dorsolateral prefrontal cortex12951.94821005510118.816110622USAGPL4372
GSE44768Cerebellum12951.94821005510118.816110622USAGPL4372
GSE122063Frontal and temporal cortex5678.5781.591634454.55819160USAGPL16699

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416