Logo Medical Science Monitor Basic Research

Call: 1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Contact Us

Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research Logo Medical Science Monitor Basic Research

20 September 2020: Meta-Analysis

Efficacy and Toxicity of Adjuvant Therapies for High-Risk Endometrial Cancer in Stage I–III: A Systematic Review and Network Meta-Analysis

Mengyin Ao 12ABCDEF , Ting Ding 12BF , Dan Tang 12E , Mingrong Xi 12E*

DOI: 10.12659/MSM.925595

Med Sci Monit 2020; 26:e925595

Table 1 Characteristics of included randomized clinical trials.

AuthorSub-categoryLocationFIGO stageInterventionSample sizeAge, years median (range)
T1T2T1T2TotalT1T2
Randall et al.GOG-249USAI–IIAB30130060163 (NR)65 (NR)
Hogberg et al. (1)NSGO-RORTCSwedenI–IIICAC19118737864 (44–79)64 (38–83)
Hogberg et al. (2)MangoSwedenII–IIIAC768015659 (42–78)58 (39–77)
Morrow et al.GOG-34USAI–II occultAC8992181NRNR
Kuoppala et al.NRFinlandI–IIIAAC728415674 (47–86)73 (47–85)
de Boer et al.PORTEC-3France, Italy, CanadaI–IIIAC33033066062 (NR)62 (NR)
Creutzberg et al.PORTEC-1NetherlandsI–IIICAD35436071466 (41–85)66 (43–90)
Keys et al.GOG-99USAI–II occultAD19020239263 (NR)63 (NR)
Blake et al.ASTEC/EN5UK, Canada, PolandI–IIBAD45245390565 (36–88)66 (31–88)
Susumu et al.JGOGJapanIC–IIICAE193192385NRNR
Maggi et al.NRItalyIC–IIICAE16617434062 (NR)63 (NR)
Sorbe et al.NRSwedenIA–ICFG264263527NRNR
Sunil et al.NRIndiaIA–IBFG252550NRNR
Nout et al.PORTEC-2DutchIB–IIAAG21421342769 (NR)70 (NR)
A – pelvic radiotherapy; B – vaginal cuff brachytherapy and chemotherapy; C – pelvic radiotherapy and chemotherapy; D – No further treatment; E – chemotherapy; F – pelvic radiotherapy and vaginal brachytherapy; G – vaginal brachytherapy.
a Based on FIGO 2009 classification;
b based on FIGO 1988 classification;
c based on FIGO 2009 classification;
NR – not reported.

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416