The Levels of Lactate, Troponin, and N-Terminal Pro-B-Type Natriuretic Peptide Are Predictors of Mortality in Patients with Sepsis and Septic Shock: A Retrospective Cohort Study

Harith Alataby; Jay Nfonoyim; Keith Diaz; Amna Al-Tkrit; Shahnaz Akhter; Sharoon David; Vishnuveni Leelaruban; Kara S. Gay-Simon; Vedatta Maharaj; Bruce Colet; Cherry Hanna; Cheryl-Ann Gomez

doi:10.12659/MSMBR.927834

01 February 2021 : Original article

The Levels of Lactate, Troponin, and N-Terminal Pro-B-Type Natriuretic Peptide Are Predictors of Mortality in Patients with Sepsis and Septic Shock: A Retrospective Cohort Study

Harith Alataby^1ADEF*, Jay Nfonoyim^12AE, Keith Diaz^12E, Amna Al-Tkrit^3EF, Shahnaz Akhter^3A, Sharoon David^3EF, Vishnuveni Leelaruban^1B, Kara S. Gay-Simon^1B, Vedatta Maharaj^1B, Bruce Colet^1B, Cherry Hanna^1B, Cheryl-Ann Gomez^1B

DOI: 10.12659/MSMBR.927834

Med Sci Monit Basic Res 2021; 27:e927834

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Table 2 Higher biomarker levels were associated with higher possibility of death as a predictor of 30-day mortality.

Variable	Odds ratio	95% CI	P-value
Lactate 4.0	3.1929	(1.98–5.14)	0.00006
Troponin >0.045	2.12741	(1.51–2.99)	0.00027
NT-proBNP >8000	2.497	(1.69–3.70)	0.00013
NT-proBNP – N-terminal pro-B-type natriuretic peptide; CI – confidence interval.

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The Levels of Lactate, Troponin, and N-Terminal Pro-B-Type Natriuretic Peptide Are Predictors of Mortality in Patients with Sepsis and Septic Shock: A Retrospective Cohort Study

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