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23 August 2021: Meta-Analysis

Periodontitis and Number of Teeth in the Risk of Coronary Heart Disease: An Updated Meta-Analysis

Shuting Gao 1BEF , Jinhui Tian 2A , Yiting Li 1CD , Tingjie Liu 1B , Ruiping Li 1C , Lan Yang 3FG* , Zhankui Xing 1AG*

DOI: 10.12659/MSM.930112

Med Sci Monit 2021; 27:e930112

Table 2 Study characteristics.

ReferenceSample sizeAge rangeControl groupStudy areaFollow-up yearPeriodontal condition/teeth number at baselineCHD assessment
2074925–74No periodontitisUSA14PeriodontitisgingivitisedentulousCHD mortality and admission to hospital
4411940–75maleNo periodontitis32-25USA6Periodontitis32-25; 24-1716-11; 10-0Incidence of fatal and non-fatal MI and sudden death
1609035–84No periodontitisCanada23PeriodontitisgingivitisedentulousRisk of fatal CHD
803225–74No periodontitis32-25USA6Periodontitisgingivitis32-25; 24-17;16-11; 10-4Fatalities, hospitalization of CHD and revascularization
996225–54No periodontitisUSA21PeriodontitisgingivitisedentulousHospital records for non-fatal events and death certificates for fatal events
2203740–84maleNo periodontitisUSA12.3PeriodontitisNonfatal MI
10038140–75 male30–55 female32-25USA1232-25; 24-17;16-11; 10-0Symptomatic nonfatal MI, fatal CHD, or sudden death
15273>35No periodontitisSweden35PeriodontitisCoronary heart disease (ICD-9 codes 410–414)
767420–89No periodontitis>25Sweden12Periodontitis>25; 25-20;19-15; 14-10;ICD mortality (ICD-8, ICD-9, and ICD-10)
308136–59 maleNo periodontitisJapan5PeriodontitisMI
844625–740–1Finland130–1; 2–45–8; 9–31; 32A history of myocardial infarction, revascularizations, or percutaneous transluminal coronary angioplasty
39863≥45 femaleNo periodontitisUSA15.7PeriodontitisMI
The sample size includes the original population, not excluding loss. CHD – coronary heart disease; MI – myocardial infarction; ICD – International Classification of Disease.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416