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02 August 2021: Meta-Analysis

Association Between Gene Polymorphisms and Risk of Preeclampsia: Systematic Review and Meta-Analysis

Manni Sun BE , Hui Jiang BF , Tao Meng AF , Peiyan Liu BC , Haiying Chen ACG*

DOI: 10.12659/MSM.930438

Med Sci Monit 2021; 27:e930438

Table 3 Main results for pooled ORs in the meta-analysis.

Genetic modelTest of associationTest of heterogeneityTest of publication bias (Egger)Type of model
OR95% CIPI2 (%)PTP
G vs A0.960.51–1.780.88767.90.0141.280.289Random
GG vs AA1.220.38–3.900.7400.00.438−1.530.225Fixed
GG vs GA1.180.32–4.340.8020.00.814−0.530.630Fixed
GG+GA vs AA0.940.53–1.670.82659.80.0411.400.256Random
GG vs GA+AA1.220.38–3.930.7430.00.479−1.400.255Fixed
T vs C1.070.48–2.380.87171.50.0150.870.474Random
TT vs CC1.080.03–4.630.92217.80.296−40.80.016Fixed
TT vs TC0.820.15–4.470.8180.00.727−2.170.275Fixed
TT+TC vs CC1.070.50–2.290.85465.90.0320.950.441Random
TT vs TC+CC1.050.24–4.570.9538.70.334−41.690.015Fixed

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416