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11 May 2021: Animal Studies

Kangfuxin Liquid Ameliorates Dextran Sulfate Sodium (DSS)-Induced Acute Ulcerative Colitis in Mice by Modulating Immune Response and Suppressing Inflammation

Miao Tang 12AEF* , Lian-Li Ni 134BEF* , Jing-Lei Xu 5C , Yu-Jia Wang 5C , Cheng-Gui Zhang 15D , Tahir Ali 6D , Xiu-Mei Wu 35C , Heng Liu 27AG , Miao He 36AG*

DOI: 10.12659/MSMBR.930887

Med Sci Monit Basic Res 2021; 27:e930887

Table 3 Histological scoring criteria.

ScoreHistological feature
0Normal colon mucosa
1Basal crypts shortened with mild edema and inflammatory cell infiltration in the histological score
2Basal crypts disappeared with moderate inflammation in the lamina propria
3Basal crypts disappeared with severe inflammation of lamina propria but surface epithelium remained
4Basal crypts and surface epithelium all disappeared with severe inflammation of mucosa, muscularis propria and submucosa of lamina propria

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416