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02 January 2022: Clinical Research

Retrospective Study of 573 Patients with Heart Failure Evaluated for Coronary Artery Disease at Toulouse University Center, France

Antoine Deney 1ABCDEF* , Vanessa Nader 12ABCDEF* , Anthony Matta 13ABCDE , Romain Itier 1CDE , Pauline Fournier 1ABCD , Olivier Lairez 1ADF , Nathalie Pizzinat 4ACD , Didier Carrié 1ACD , Frédéric Boal 4ACD , Michel Galinier 1ACD , Oksana Kunduzova 4ACD , Rania Azar 2ACD , Jerome Roncalli 14ABCDEFG*

DOI: 10.12659/MSM.934804

Med Sci Monit 2022; 28:e934804

Table 6 Characteristics of ischemic heart failure (IHF) group stratified by type of heart failure.

CAD-populationN=320HFpEFN=50HFrEFN=270P-value
Age70.95±10.40474.04±8.94970.38±10.5670.022
Male sex269 (84.06%)42 (84.00%)227 (84.07%)0.990
BMI26.28±4.8627.39±5.6326.08±4.690.081
Atrial fibrillation95 (29.69%)11 (22.00%)84 (31.11%)0.195
Chronic kidney disease182 (56.87%)27 (54.00%)155 (57.41%)0.479
Dyslipidemia106 (33.13%)25 (50.00%)81 (30.00%)0.007
Diabetes113 (35.31%)19 (38.00%)94 (34.81%)0.729
Hypertension198 (66.9%)36 (72.00%)162 (60.00%)0.123
Smoking85 (26.56%)8 (16.00%)77 (28.52%)0.053
Family history47 (14.69%)7 (14.00%)40 (14.81%)0.840
Valvopathy131 (40.93%)17 (34.00%)114 (42.22%)0.305
RVD58 (18.13%)3 (6.00%)55 (20.37%)0.1
TAPSE17.29±4.4717.88±2.6917.26±4.550.706
PAPSE41.38±14.0139.67±11.1141.41±14.300.772
Pacemaker26 (8.13%)8 (12.00%)20 (7.41%)0.268
Defibrillator26 (8.13%)1 (2%)25 (9.26%)0.096
NYHA
 113 (4.06%)013 (4.81%)0.339
 283 (25.94%)13 (26.00%)70 (25.93%)
 387 (27.19%)14 (28.00%)73 (27.04%)
 425 (7.81%)1 (2.00%)24 (8.89%)
Systolic blood pressure129.77±23.12139.73±21.452127.95±22.990.003
Diastolic blood pressure74.50±14.0973.83±19.7674.62±14.350.742
Heart rate79.25±20.78)74.43±19.2180.13±20.970.110
Troponin169.84±652.3272.15±62.86186.97±705.820.470
NT-ProBNP5889.47±8758.003724.19±6747.796135.28±9017.840.127
β-blockers194 (60.63%)24 (48.00%)170 (62.96%)0.047
Diuretics191 (59.69%)29 (58.00%)162 (60.00%)0.768
Mineralocorticoids55 (17.19%)7 (14.00%)48 (17.78%)0.552
ACE/ARA175 (54.69%)27 (54.00%)148 (54.81%)0.915
ARNI24 (7.50%)024 (8.89%)0.016
Ivabradine5 (1.56%)05 (1.85%)1
SAPT128 (40.00%)25 (50.00%)103 (38.15%)0.189
DAPT43 (13.44%)7 (14.00%)36 (13.33%)0.958
DOAC+AVK1 (0.31%)01 (0.37%)1
AAP+OAC30 (9.37%)5 (10.00%)25 (9.26%)0.677
β-blockers267 (83.43%)32 (64.00%)235 (87.04%)
Diuretics245 (76.56%)37 (74.00%)208 (77.04%)0.514
Mineralocorticoids117 (36.56%)10 (20.00%)107 (39.63%)0.007
ACE/ARA182 (56.87%)37 (74.00%)145 (53.70%)0.011
ARNI66 (20.62%)1 (2.00%)65 (24.07%)
Ivabradine11 (3.43%)1 (2.00%)10 (3.70%)1
SAPT79 (24.69%)22 (44.00%)57 (21.11%)0.001
DAPT201 (62.81%)27 (54.00%)174 (64.44%)0.115
DOAC+AVK111 (34.69%)15 (30.00%)96 (35.55%)0.398
AAP+OAC77 (24.06%)9 (18.00%)68 (25.18%)0.281
BMI – body mass index; APT – single anti-platelet therapy; DAPT – dual anti-platelet therapy; DOAC – direct oral anti-coagulant; AP+OAC – anti-platelet +oral anti-coagulant.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416