08 March 2023: Human Study
Study of 60 Adult Patients to Compare Standard Postoperative Clinical Assessment with Train-of-Four Ratio ≥0.9 on Patient Outcomes Using Postoperative Spirometry and Neuromuscular Function Measurements Following Extubation
Chunlong Chen AEF , Qingzhen Liu CD , Hong Fan BD , Zhiyang Yu CF , Xueyan Leng B , Lidong Zhang ADF , Zhiqiang Zhou ADE*DOI: 10.12659/MSMBR.938849
Med Sci Monit Basic Res 2023; 29:e938849
Table 2 Intraoperative management and anesthetic and relaxant consumption.
| Clinical assessment group n=30 | TOF group n=30 | P value | |
|---|---|---|---|
| Anesthesia time, min | 129 (59) | 146 (52) | 0.252 |
| Surgery time, min | 107 (59) | 122 (54) | 0.308 |
| Anesthesia maintenance | 0.136 | ||
| Volatile+propofol | 20 (66.7) | 10 (33.3) | |
| Total intravenous | 25 (83.3) | 5 (16.7) | |
| Propofol | |||
| Total amount, mg | 743 (394) | 807 (357) | 0.513 |
| Amount/hour, mghr-1 | 358 (131) | 329 (87) | 0.330 |
| Sufentanyl amount, ug | 50 [38.8–50] | 50 [40–50] | 0.229 |
| Remifentanyl | |||
| Total amount, ug | 500 [385–800] | 500 [388–1000] | 0.546 |
| Amount/hour, ughr-1 | 253 (82) | 251 (124) | 0.945 |
| Cisatracurium | |||
| Total amount, mg | 22.5 (9.7) | 21.9 (10.2) | 0.830 |
| Amount/hour, mghr-1 | 11.9 (6.3) | 9.3 (4.1) | 0.060 |
| Blood loss, mL | 75 [45–200] | 150 [87–225] | 0.194 |
| Total fluids, mL | 1000 [800–1225] | 1000 [800–1500] | 0.530 |
| PACU RASS score | |||
| @10 min | 0 [0–0] | 0 [−1–0] | 0.318 |
| @30 min | 0 [0–0] | 0 [0–0] | 0.750 |
| @50 min | 0 [0–0] | 0 [0–0] | 0.739 |
| PACU – Postanesthesia Care Unit; RASS – Richman Agitation Sedation Scale; @10 min – time point of 10 min after extubation; @30 min – time point of 30 min after extubation; @50 min, time point of 50 min after extubation. Data are shown as mean (standard deviation), number (%), or median [interquartile range]. | |||