Logo Medical Science Monitor

Call: +1.631.470.9640
Mon - Fri 10:00 am - 02:00 pm EST

Contact Us

Logo Medical Science Monitor Logo Medical Science Monitor Logo Medical Science Monitor

29 October 2014 : Original article  

Cerebrovascular Reserve may be a More Accurate Predictor of Stroke than Degree of ICA or MCA Stenosis

Mingyong LiuBCDEF, Lichun ZhouAG

DOI: 10.12659/MSM.892377

Med Sci Monit 2014; 20:2082-2087

Abstract

BACKGROUND: It is currently unclear whether the degree of stenosis or the cerebrovascular reserve (CVR) is a better predictor of ischemic stroke.

MATERIAL AND METHODS: In this study, CVR was measured by perfusion computed tomography with inhalation of 5% CO2 in 37 symptomatic patients with internal carotid artery (ICA) or middle cerebral artery (MCA) stenosis or occlusion. Patients were divided into groups according to the degree of stenosis: ≥70% stenosis (stenosis group 1) or <70% stenosis (stenosis group 2); and according to CVR: ≥10% CVR (CVR group 1) or <10% CVR (CVR group 2). All patients were given medical treatment.

RESULTS: During a mean follow-up period of 56.9 months (range 24–73 months), recurrent ipsilateral ischemic stroke occurred in 7 patients. Ischemic stroke occurred in 0 of 19 patients in CVR group 1 (annual risk 0%), 7 of 18 patients in CVR group 2 (annual risk 7.7%), 3 of 18 patients in stenosis group 1 (annual risk 3.3%), and 4 of 19 patients in stenosis group 2 (annual risk 4.7%). Comparisons using Pearson’s chi-square test showed a significant difference in the rate of ischemic stroke between CVR group 1 and CVR group 2 (odds ratio 1.700; 95% confidence interval 1.142–2.530; P=0.003), but no significant difference between stenosis group 1 and stenosis group 2 (P=0.691).

CONCLUSIONS: Cerebrovascular reserve may be a more accurate predictor of stroke than degree of ICA or MCA stenosis

Keywords: Aged, 80 and over, Brain - physiopathology, Constriction, Pathologic - physiopathology, Middle Cerebral Artery - pathology, Recurrence, Stroke - physiopathology

Add Comment 0 Comments

Editorial

01 March 2024 : Editorial  

Editorial: First Regulatory Approvals for CRISPR-Cas9 Therapeutic Gene Editing for Sickle Cell Disease and Transfusion-Dependent β-Thalassemia

Dinah V. Parums

DOI: 10.12659/MSM.944204

Med Sci Monit 2024; 30:e944204

0:00

In Press

18 Mar 2024 : Clinical Research  

Sexual Dysfunction in Women After Tibial Fracture: A Retrospective Comparative Study

Med Sci Monit In Press; DOI: 10.12659/MSM.944136  

0:00

21 Feb 2024 : Clinical Research  

Potential Value of HSP90α in Prognosis of Triple-Negative Breast Cancer

Med Sci Monit In Press; DOI: 10.12659/MSM.943049  

22 Feb 2024 : Review article  

Differentiation of Native Vertebral Osteomyelitis: A Comprehensive Review of Imaging Techniques and Future ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943168  

23 Feb 2024 : Clinical Research  

A Study of 60 Patients with Low Back Pain to Compare Outcomes Following Magnetotherapy, Ultrasound, Laser, ...

Med Sci Monit In Press; DOI: 10.12659/MSM.943732  

Most Viewed Current Articles

16 May 2023 : Clinical Research  

Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...

DOI :10.12659/MSM.940387

Med Sci Monit 2023; 29:e940387

0:00

17 Jan 2024 : Review article  

Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron Variant

DOI :10.12659/MSM.942799

Med Sci Monit 2024; 30:e942799

0:00

14 Dec 2022 : Clinical Research  

Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase Levels

DOI :10.12659/MSM.937990

Med Sci Monit 2022; 28:e937990

0:00

01 Jan 2022 : Editorial  

Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...

DOI :10.12659/MSM.935952

Med Sci Monit 2022; 28:e935952

0:00

Your Privacy

We use cookies to ensure the functionality of our website, to personalize content and advertising, to provide social media features, and to analyze our traffic. If you allow us to do so, we also inform our social media, advertising and analysis partners about your use of our website, You can decise for yourself which categories you you want to deny or allow. Please note that based on your settings not all functionalities of the site are available. View our privacy policy.

Medical Science Monitor eISSN: 1643-3750
Medical Science Monitor eISSN: 1643-3750