15 January 2008
Rhabdomyolysis in sertraline intoxication: a case report
Sule Akin, Anis Aribogan, Daniel R. BrownAm J Case Rep 2008; 9:23-26 :: ID: 690775
Abstract
Background: Sertraline is a selective serotonin reuptake inhibitor used for the treatment of depression. This case report presents a patient with sertraline overdos and serotonin syndrome complicated by rhabdomyolysis.
Case Report: A 31-year-old male patient was brought to the hospital by relatives 48 hours after taking 42 tablets of sertaline HCl (Lustral, 50 mg/tablet, Pfizer) during a suicide attempt. He was generally lethargic but did have brief episodes of agitation without apparent precipitating factors. The patient was admitted to intensive care unit after laboratory evaluation indicated acute renal failure and rhabdomyolysis. Physical exam was notable for hyperreflexia and inducible clonus. Therapy included administration of cyproheptadine for serotonin syndrome and forced diuresis for renal failure by administration of crystalloids and furosemide. The patient’s neurological and biochemical profile improved and the patient was discharged on the 10[sup]th [/sup]day of admission without residual organ impairment.
Conclusions: This case is consistent with an unusual presentation of serotonin syndrome 48 hours following an overdose of sertraline.
Keywords: Sertraline, Serotonin Syndrome, rhabdomyolysis
In Press
12 Mar 2024 : Case report
Successful Treatment of Lithium-Induced Nephrogenic Diabetes Insipidus with Celecoxib: A Promising Therapeu...Am J Case Rep In Press; DOI: 10.12659/AJCR.943244
13 Mar 2024 : Case report
Recurrent Marginal Zone Lymphoma with Bone Marrow Involvement Detected by ¹⁸F-FDG PET/CT and Biopsy: A Diag...Am J Case Rep In Press; DOI: 10.12659/AJCR.943275
13 Mar 2024 : Case report
Unveiling the Temporal Aspect of MRI Tattoo Reactions: A Prospective Evaluation of a Newly-Acquired Tattoo ...Am J Case Rep In Press; DOI: 10.12659/AJCR.943411
13 Mar 2024 : Case report
Cardiac and Intramuscular Metastases Following Nephroureterectomy for Metachronous Urothelial CarcinomaAm J Case Rep In Press; DOI: 10.12659/AJCR.942864
Most Viewed Current Articles
07 Mar 2024 : Case report
Neurocysticercosis Presenting as Migraine in the United StatesDOI :10.12659/AJCR.943133
Am J Case Rep 2024; 25:e943133
10 Jan 2022 : Case report
A Report on the First 7 Sequential Patients Treated Within the C-Reactive Protein Apheresis in COVID (CACOV...DOI :10.12659/AJCR.935263
Am J Case Rep 2022; 23:e935263
19 Jul 2022 : Case report
Atlantoaxial Subluxation Secondary to SARS-CoV-2 Infection: A Rare Orthopedic Complication from COVID-19DOI :10.12659/AJCR.936128
Am J Case Rep 2022; 23:e936128
23 Feb 2022 : Case report
Penile Necrosis Associated with Local Intravenous Injection of CocaineDOI :10.12659/AJCR.935250
Am J Case Rep 2022; 23:e935250