29 December 2019 : Clinical Research
Incidence of Stroke and Mortality in Chinese Patients with Sleep-Breathing Disorders: A Clinical Population-Based (CPB) Study
Tao Hu12ACDF, Yang Gu2ABCF, Yan Xu2CDF, Juebo Yu3BCDF, Feng Wu2BDFG, Rui Chen1DEFG*DOI: 10.12659/MSM.918120
Med Sci Monit 2019; 25:10129-10135
Abstract
BACKGROUND: Sleep-breathing disorders are associated with inflammatory, metabolic, and vascular diseases. The objective of this study was to investigate the incidence of stroke and death in patients with sleep-breathing disorders.
MATERIAL AND METHODS: The anthropometric characteristics, demographic data, and incidence of stroke of 1492 Chinese patients with mild, moderate, or severe sleep apnea were collected. The apnea-hypopnea index was used to define sleep-breathing disorders. Imaging modalities were used to validate the diagnosis of stroke. Death during hospitalization or during follow-up was noted. Multivariate analysis was performed for the incidence of stroke and mortality at the 95% of confidence level.
RESULTS: Among enrolled patients, 401 (27%) patients had at least 1 event of stroke. Patients who had at least 1 event of stroke were more likely to be younger (p<0.0001), female (p=0.0013), and to have comorbidities. Among enrolled patients, 127 died due to stroke or other diseases. Sixteen of the patients who died had no stroke event(s) and 111 patients who died had at least 1 event of stroke. Stroke events (p=0.023) and biomedical burden of patients were associated with the death of patients with sleep-breathing disorders.
CONCLUSIONS: Age, sex, and the other existing disease(s) of patients with sleep-breathing disorders may be associated with stroke event(s). Also, stroke event(s) and comorbidities may be associated with mortality in this Chinese population.
Keywords: Mortality, Polysomnography, Sleep, Sleep Apnea Syndromes, Sleep apnea, obstructive, Stroke, Adolescent, Asians, Incidence, Multivariate Analysis, young adult
Editorial
01 May 2024 : Editorial
Editorial: First Regulatory Approval for Adoptive Cell Therapy with Autologous Tumor-Infiltrating Lymphocytes (TILs) – Lifileucel (Amtagvi)DOI: 10.12659/MSM.944927
Med Sci Monit 2024; 30:e944927
In Press
14 Mar 2024 : Clinical Research
Renal Dysfunction Increases Risk of Adverse Cardiovascular Events in 5-Year Follow-Up Study of Intermediate...Med Sci Monit In Press; DOI: 10.12659/MSM.943956
15 Mar 2024 : Clinical Research
Impact of One-Lung Ventilation on Oxygenation and Ventilation Time in Thoracoscopic Heart Surgery: A Compar...Med Sci Monit In Press; DOI: 10.12659/MSM.943089
14 Mar 2024 : Clinical Research
Differential DHA and EPA Levels in Women with Preterm and Term Births: A Tertiary Hospital Study in IndonesiaMed Sci Monit In Press; DOI: 10.12659/MSM.943895
15 Mar 2024 : Clinical Research
Evaluation of an Optimized Workflow for the Radiofrequency Catheter Ablation of Paroxysmal Atrial FibrillationMed Sci Monit In Press; DOI: 10.12659/MSM.943526
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952