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07 July 2022: Laboratory Research

Cytotoxicity, Apoptosis, Migration Inhibition, and Autophagy-Induced by Crude Ricin from Seeds in A549 Lung Cancer Cell Lines

Irma Erika Herawati 12ABCDEF , Ronny Lesmana 345ABDEF , Jutti Levita ABD1EF , Anas Subarnas 1ABCDEFG*

DOI: 10.12659/MSMBR.936683

Med Sci Monit Basic Res 2022; 28:e936683

Figure 3 Western blot analysis of caspase cascade-related proteins in A549 lung cells treated with cisplatin and CR. (A) Representative blots of caspase-9 and -3 were determined in A549 cells treated with cisplatin and CR at 36 h; (B) Densitometry protein levels of caspase-9, cleaved caspase-9, caspase-3, and cleaved caspase-3, measured using Image Studio Digits v. 5.2. and presented as a bar graph. The data are presented as mean±standard error minimum (SEM) (n=3). A one-way ANOVA followed by Tukey’s post-hoc test was conducted. * P<0.05.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416