22 December 2005
Recent advances in the pathological basis and experimental management of impaired wound healing due to total-body irradiation.
Chun-Meng Shi, Yong-Ping Su, Tian-Min ChengMed Sci Monit 2006; 12(1): RA1-4 :: ID: 443207
Abstract
Combined radiation and wound injury (CRWI) occurs in nuclear attacks andsevere nuclear accidents. The possibility of radiological terrorist attack further emphasizes the significanceof studies on CRWI. This kind of skin wound is very complex and difficult to heal since a high dose oftotal-body irradiation could delay wound healing and cause bone marrow dysplasia. Since the 1990s, thestudy of impaired wound healing due to total-body irradiation (TBI) has been emphasized in China. Inthis article, the pathological basis of the wound-healing process after TBI are reviewed and experimentalmanagement using traditional agents, growth factors, stem cells, and allo-skin transplantation in thiskind of healing-impaired wound is also discussed.
Keywords: Growth Substances - metabolism, Skin Diseases - therapy, Skin Transplantation, Stem Cells - physiology, Whole-Body Irradiation - adverse effects, Wound Healing - radiation effects
Editorial
01 April 2024 : Editorial
Editorial: Forty Years of Waiting for Prevention and Cure of HIV Infection – Ongoing Challenges and Hopes for Vaccine Development and Overcoming Antiretroviral Drug ResistanceDOI: 10.12659/MSM.944600
Med Sci Monit 2024; 30:e944600
In Press
08 Mar 2024 : Laboratory Research
Evaluation of Retentive Strength of 50 Endodontically-Treated Single-Rooted Mandibular Second Premolars Res...Med Sci Monit In Press; DOI: 10.12659/MSM.944110
11 Mar 2024 : Clinical Research
Comparison of Effects of Sugammadex and Neostigmine on Postoperative Neuromuscular Blockade Recovery in Pat...Med Sci Monit In Press; DOI: 10.12659/MSM.942773
12 Mar 2024 : Clinical Research
Comparing Neuromuscular Blockade Measurement Between Upper Arm (TOF Cuff®) and Eyelid (TOF Scan®) Using Miv...Med Sci Monit In Press; DOI: 10.12659/MSM.943630
11 Mar 2024 : Clinical Research
Enhancement of Frozen-Thawed Human Sperm Quality with Zinc as a Cryoprotective AdditiveMed Sci Monit In Press; DOI: 10.12659/MSM.942946
Most Viewed Current Articles
17 Jan 2024 : Review article
Vaccination Guidelines for Pregnant Women: Addressing COVID-19 and the Omicron VariantDOI :10.12659/MSM.942799
Med Sci Monit 2024; 30:e942799
14 Dec 2022 : Clinical Research
Prevalence and Variability of Allergen-Specific Immunoglobulin E in Patients with Elevated Tryptase LevelsDOI :10.12659/MSM.937990
Med Sci Monit 2022; 28:e937990
16 May 2023 : Clinical Research
Electrophysiological Testing for an Auditory Processing Disorder and Reading Performance in 54 School Stude...DOI :10.12659/MSM.940387
Med Sci Monit 2023; 29:e940387
01 Jan 2022 : Editorial
Editorial: Current Status of Oral Antiviral Drug Treatments for SARS-CoV-2 Infection in Non-Hospitalized Pa...DOI :10.12659/MSM.935952
Med Sci Monit 2022; 28:e935952