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30 July 2020: Clinical Research

Fiber Type-Specific Morphological and Cellular Changes of Paraspinal Muscles in Patients with Severe Adolescent Idiopathic Scoliosis

Xiexiang Shao 1ABCEF* , Jian Chen 1ABCF* , Jingfan Yang 1ADFG* , Wenyuan Sui 1BDFG , Yaolong Deng 1BCEF , Zifang Huang 2BCE , Ping Hu 3ACEG* , Junlin Yang 1ABCDEG*

DOI: 10.12659/MSM.924415

Med Sci Monit 2020; 26:e924415

Table 4 Correlation analysis between clinical parameters and the bilateral differences of fiber type specific morphological/cellular characteristics.

Age at initiationCobb angleAVTCB
rP valuerP valuerP valuerP value
Difference of type I numerical proportion−0.1200.711−0.0020.996−0.4940.103−0.1670.603
Difference of type I area proportion−0.1980.537−0.0610.850−0.1820.5710.0910.779
Ratio of CSA
 Type I0.0040.991* 0.4970.1000.0400.901
 Type II−0.1720.593* 0.3220.307−0.2690.398
 Total0.0070.982* 0.4380.155−0.1800.576
Difference of myonuclei density
 Type I−0.0710.8260.3020.341* −0.1500.641
 Type II0.1080.737−0.1750.587−0.1330.680−0.3290.297
Difference of total SC density
 Type I−0.2280.4760.3510.263* 0.4650.127
 Type II0.1500.6430.2660.403* 0.0880.787
Difference of activated SC density
 Type I−0.1160.7200.4950.102* 0.0530.870
 Type II0.2250.4820.2690.399−0.0250.940−0.5230.081
AVT – apical vertebrae translation; CB – coronal balance; CSA – cross sectional area; SC – satellite cell.
* Significant if value

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416