26 May 2021>: Laboratory Research
Cytotoxicity and Antiplasmodial Properties of Different Peel Extracts
Rudi Hendra 12ABCDEFG* , Rohimatul Khodijah 1B , Rianti Putri 1BC , Riezki Amalia 23BC , Yuli Haryani 1DF , Hilwan Yuda Teruna 1DEF , Rizky Abdulah 23DEFDOI: 10.12659/MSMBR.931118
Med Sci Monit Basic Res 2021; 27:e931118
Table 1 Toxicity, cytotoxicity, and antiplasmdodial activity of peels of H. polyrhizus extracts.
Extract | Yield (% g/g fresh sample) | Toxicity (LC50; μg/mL) | Cytotoxicity (IC50; μg/mL) | Antiplasmodial (IC50; μg/mL) | |
---|---|---|---|---|---|
SK-OV-3 | HeLa | ||||
Pigment | 0.82 | >1000 | >1000 | >1000 | >100 |
-Hexane | 1.04 | 23.6±0.40 | >1000 | >1000 | 6.51±0.49 |
Dichloromethane | 1.02 | 10.32±0.13 | 560.86±0.63 | >1000 | 2.13±0.42 |
Ethyl acetate | 2.26 | 148.93±0.57 | >1000 | >1000 | >100 |
SK-OV-3 – ovarian cancer cell line; HeLa – cervical cancer cell line. The biological activities were tested in triplicate and reported as mean±standard deviation. |