27 July 2021>: Laboratory ResearchAgron Bytyqi 1BDE , Xhevdet Aliu 2AD , Merita Barani 2BDF , David Stubljar 3CDE , Tomislav Jukic 4CDE , Andrej Starc 5CDE , Sokol Krasniqi 6ABDE*
Med Sci Monit Basic Res 2021; 27:e932492
Table 1 Antimicrobial effectiveness of diode laser irradiation with mean percentage of dead Enterococcus faecalis and Streptococcus mitis cells.
|Periapical lesion defect||Treatment||% of dead bacteria||P-value|
|E. faecalis||S. mitis|
|6 mm,a||Laser 5 min,b||73.65±5.80||78.74±3.58||0.002|
|Laser 3 min,b||54.57±3.39||52.84±2.45||0.285|
|Laser 1 min,b||46.71±3.65||47.65±3.49||0.557|
|10 mm,a||Laser 5 min,b||60.97±1.12||59.58±2.34||0.387|
|Laser 3 min,b||47.39±2.09||47.88±3.05||0.763|
|Laser 1 min,b||40.34±1.56||40.18±1.33||0.923|
|14 mm,a||Laser 5 min,b||49.03±3.72||50.82±2.04||0.270|
|Laser 3 min,b||40.92±1.24||41.68±1.92||0.640|
|Laser 1 min,b||32.71±1.81||34.03±1.16||0.414|
|Superscript letters denote statistically significant differences obtained with post hoc testing.|
a Lesion dimensions showed different overall results. Laser had greater disinfecting effect in smaller lesions showing higher percent of dead and cells (
b Five-minute laser irradiation showed differences in disinfection effectiveness compared to 3-min or 1-min laser irradiation in both microorganisms. Three-minute laser irradiation was more effective than 1-min irradiation. One-minute laser irradiation was the least effective, but it showed a statistically significant difference compared with the control nontreatment group;
c Interaction between lesion dimensions and laser irradiation time were correlated.
To obtain similar disinfecting efficacy as for smaller lesions, a longer irradiation time should be applied for larger lesions.