27 July 2021: Laboratory Research
Disinfection of Infected Artificial Dental Periapical Lesions with Diode Laser: An In Vitro Study
Agron Bytyqi 1BDE , Xhevdet Aliu 2AD , Merita Barani 2BDF , David Stubljar 3CDE , Tomislav Jukic 4CDE , Andrej Starc 5CDE , Sokol Krasniqi 6ABDE*DOI: 10.12659/MSMBR.932492
Med Sci Monit Basic Res 2021; 27:e932492
Table 1 Antimicrobial effectiveness of diode laser irradiation with mean percentage of dead Enterococcus faecalis and Streptococcus mitis cells.
| Periapical lesion defect | Treatment | % of dead bacteria | P-value | |
|---|---|---|---|---|
| E. faecalis | S. mitis | |||
| 6 mm,a | Laser 5 min,b | 73.65±5.80 | 78.74±3.58 | 0.002 |
| Laser 3 min,b | 54.57±3.39 | 52.84±2.45 | 0.285 | |
| Laser 1 min,b | 46.71±3.65 | 47.65±3.49 | 0.557 | |
| Positive control,b | 26.47±1.42 | 29.01±3.92 | 0.413 | |
| 10 mm,a | Laser 5 min,b | 60.97±1.12 | 59.58±2.34 | 0.387 |
| Laser 3 min,b | 47.39±2.09 | 47.88±3.05 | 0.763 | |
| Laser 1 min,b | 40.34±1.56 | 40.18±1.33 | 0.923 | |
| Positive control,b | 23.95±2.27 | 25.28±0.99 | 0.633 | |
| 14 mm,a | Laser 5 min,b | 49.03±3.72 | 50.82±2.04 | 0.270 |
| Laser 3 min,b | 40.92±1.24 | 41.68±1.92 | 0.640 | |
| Laser 1 min,b | 32.71±1.81 | 34.03±1.16 | 0.414 | |
| Positive control,b | 25.44±0.77 | 25.07±0.11 | 0.895 | |
| Superscript letters denote statistically significant differences obtained with post hoc testing. a Lesion dimensions showed different overall results. Laser had greater disinfecting effect in smaller lesions showing higher percent of dead and cells ( b Five-minute laser irradiation showed differences in disinfection effectiveness compared to 3-min or 1-min laser irradiation in both microorganisms. Three-minute laser irradiation was more effective than 1-min irradiation. One-minute laser irradiation was the least effective, but it showed a statistically significant difference compared with the control nontreatment group; c Interaction between lesion dimensions and laser irradiation time were correlated. To obtain similar disinfecting efficacy as for smaller lesions, a longer irradiation time should be applied for larger lesions. | ||||