07 July 2022 : Laboratory Research
Cytotoxicity, Apoptosis, Migration Inhibition, and Autophagy-Induced by Crude Ricin from Ricinus communis Seeds in A549 Lung Cancer Cell Lines
Irma Erika Herawati12ABCDEF, Ronny Lesmana345ABDEF, Jutti Levita
1ABDEF, Anas Subarnas1ABCDEFG*
DOI: 10.12659/MSMBR.936683
Med Sci Monit Basic Res 2022; 28:e936683
Table 2 Percentage of gap enclosure induced by cisplatin and crude ricin (CR) in A549 lung cancer cell lines.
| Concentration (ppm) | Gap enclosure (%) | |
|---|---|---|
| 24 h | 48 h | |
| Control | 42.15±0.10 | 83.30±0.19 |
| Cisplatin 0.1 | 44.49±0.10 | 82.41±0.17 |
| Cisplatin 0.5 | 45.34±0.07 | 83.95±0.17 |
| Cisplatin 1.0 | 18.21±0.02 | 3.28±0.01 |
| CR 0.1 | 44.88±0.02 | 82.57±0.05 |
| CR 0.5 | 6.84±0.03 | 7.96±0.08 |
| CR 1.0 | 1.45±0.02 | 3.10±0.03 |
| Gap enclosure was measured using ImageJ. | ||