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07 August 2013 : Original article  

Flap prefabrication using high-density porous polyethylene in an animal model – an experimental study

Łukasz KrakowczykABEF, Adam MaciejewskiAD, Cezary SzymczykFG, Maciej GrajekCF, Ewa StobieckaCD, Stanisław PółtorakDG

DOI: 10.12659/MSMBR.889214

Med Sci Monit Basic Res 2013; 19:210-213


BACKGROUND: The search for new surgical flap techniques and modifications of already existing ones is gaining increasing popularity. Progress in flap designing and harvesting have improved the functional and aesthetic results, especially in head and neck reconstruction.

MATERIAL AND METHODS: Ten pigs were used in this study. In the first operation, high-density porous polyethylene prefabrication was performed bilaterally in all pigs. After 8 weeks, each prefabricated complex was explored, resected, and macroscopically evaluated.

RESULTS: All of 20 prefabricated flaps survived. No serious surgical complications were observed. In 2 cases there was chronic inflammation and in 4 cases there was instability of the implant.

CONCLUSIONS: After this experimental study, we believe that the use of high-density porous polyethylene in flap prefabrication may be a good option for reconstruction of 3-dimensional defects, especially in patients with limited donor tissues.

Keywords: Surgical Flaps, Swine, Reconstructive Surgical Procedures - methods, Postoperative Complications - epidemiology, Polyethylene, Models, Animal, Tissue and Organ Harvesting - methods

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416