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20 January 2021: Meta-Analysis

Association Between Mitochondrial DNA Copy Number and Head and Neck Squamous Cell Carcinoma: A Systematic Review and Dose-Response Meta-Analysis

Zhu Zhu 1ABCDEF , Yixiu Liu 2B , Didi Wu 1C , Hongpeng Wang 2ABCDEF*

DOI: 10.12659/MSM.928327

Med Sci Monit 2021; 27:e928327

Supplementary Table 1 Supplementary information of included studies.

StudyAge (years)Gender (% Male)Smoking (% ever)Drinking (% ever)CategorizationNumber
Case/controlCase/controlCase/controlCaseControl
Kim 200462.4/38.8No
Jiang 200556.8/61.871 (75.5)/413 (63.3)52 (79.1)/405 (62.0)No
Mondal 201358/5698 (79.0)/101 (72.1)89 (71.7)/75 (53.4)By quartile
 ≤0.15843
 >0.1–13542
 >1–101929
 >101226
Cheau-Feng Lin 201456±11.9/−75 (100)/−61 (81.3)/−50 (66.7)/−No
Dang 201460.75±9.64/−197 (96.6)/−141 (69.1)/−No
Ghosh 201449 (76.6)/79 (79.0)43 (67.2)/27 (27.0)44 (68.8)By quartile
/49 (49.0) ≤0.23129
 >0.2–21527
 >2–121125
 >12719
He 201457.3±12.4/58.5±11.487 (60.8)/215 (60.2)83 (58.0)/175 (49.0)85 (59.4)By median
/108 (30.3)56186
 ≥1.0887171
Wang 201861.07±10.88/59.62±9.35357 (62.6)/374 (62.7)258 (45.3)/253 (42.4)252 (44.2)By quartile
/192 (32.2)165150
 1.93–3.5089149
 3.50–11.22119149
 >11.22197149

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416