H-Index
10
Scimago Lab
powered by Scopus
eISSN: 2325-4416
call: +1.631.470.9640
Mon-Fri 10 am - 2 pm EST

Logo

MSMbanner
AmJCaseRep

Annals
ISI-Home

Get your full text copy in PDF

Effect of Bariatric Surgery on Semen Parameters: A Systematic Review and Meta-Analysis

Yong Wei, Quanbing Chen, Wenhui Qian

(Department of Urology, Nanjing Gaochun People’s Hospital, Nanjing, Jiangsu, China (mainland))

Med Sci Monit Basic Res 2018; 24:188-197

DOI: 10.12659/MSMBR.910862


BACKGROUND: The present systematic review and meta-analysis was performed to explore the possible effect of bariatric surgery on semen parameters.
MATERIAL AND METHODS: Studies on the effect of bariatric surgeries on semen parameters were collected by searching Cochrane Library, PUBMED, EMBASE, MEDLINE, and CNKI databases. We extracted information on essential data and outcome measures, including study design, bariatric surgery, and semen parameters at baseline and after the surgery from the included studies, and STATA 12.0 software was applied to conduct the meta-analysis. Predefined subgroup analyses were also conducted by study design and bariatric surgical procedures. The standard mean difference (SMD) was calculated to estimate the effect on semen parameters.
RESULTS: After the literature search, 6 articles that fulfilled the inclusion criteria were included in the present meta-analysis. The results revealed that patients who had undergone gastric bypass surgery had an increase in semen volume (SMD (95%CI)=0.583 (0.121–1.045), p=0.013). However, the seminal concentration (overall, SMD (95%CI)=–0.123 (–0.418–0.173), p=0.416) and the semen progressive motility (overall SMD (95%CI)=0.148 (–0.148–0.444), p=0.328) remained unchanged after the bariatric surgery. Nevertheless, semen normal morphology experienced an increase in the subgroup of prospective design and sleeve gastrectomy (prospective study, SMD (95%CI)= 0.385 (0.074–0.697), p=0.015, sleeve gastrectomy, SMD (95%CI)=0.880 (0.465–1.296), p=0.000; overall, SMD (95%CI)=0.372 (0.068–0.677), p=0.017).
CONCLUSIONS: In conclusion, based on the limitations of the present meta-analysis, definite conclusions cannot be reached regarding the possible effect of bariatric surgery on semen parameters.

This paper has been published under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) allowing to download articles and share them with others as long as they credit the authors and the publisher, but without permission to change them in any way or use them commercially.
I agree