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04 August 2020: Database Analysis

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach

Shuang Song 12ABCDEF , Bin Li 12A , Zhen Jia 12C , Li Guo 12AG*

DOI: 10.12659/MSM.923547

Med Sci Monit 2020; 26:e923547

Figure 2 Boxplot of multigroup comparisons of sirtuin-related RNA levels among the Huntington’s disease, Alzheimer’s disease (AD) and control groups in dataset GSE33000. At the top of the figure, sirtuin gene symbols indicate subgroup information; below, Kruskal-Wallis P-values among the Huntington’s disease, AD, and control groups are shown. At the bottom of the figure, boxes representing the sirtuin-related RNA expression values from the microarray are shown, and the post hoc subgroup comparison results are shown between the RNA expression boxes and Kruskal-Wallis P-values. **** P<0.0001, *** P<0.001, ** P<0.01, * P<0.05 and ns P≥0.05. ND indicates “no dementia” as the control group.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416