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04 August 2020: Database Analysis

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach

Shuang Song 12ABCDEF , Bin Li 12A , Zhen Jia 12C , Li Guo 12AG*

DOI: 10.12659/MSM.923547

Med Sci Monit 2020; 26:e923547

Figure 5 Histogram of the differentially expressed genes (DEGs) and the SIRT3-related DEGs in 8 datasets. (A) Histogram of the Alzheimer’s disease (AD)-related DEGs in 8 datasets. The bars parallel to the X axis represent gene counts in each dataset, and the bars parallel to the Y axis represent the intersection gene counts of selected datasets. The dots below the X axis indicate which datasets make up the intersection. (B) Histogram of the SIRT3-related DEGs in 6 datasets, as there was no SIRT3-related DEG in GSE44768 and SIRT3 did not have a significant difference between the AD and control groups in GSE132903.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416