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04 August 2020: Database Analysis

Sirtuin 3 mRNA Expression is Downregulated in the Brain Tissues of Alzheimer’s Disease Patients: A Bioinformatic and Data Mining Approach

Shuang Song 12ABCDEF , Bin Li 12A , Zhen Jia 12C , Li Guo 12AG*

DOI: 10.12659/MSM.923547

Med Sci Monit 2020; 26:e923547

Figure 7 Box plot for enriched Gene Ontology biological process, cellular component, and molecular function categories of the Alzheimer’s disease (AD)-related differentially expressed genes (DEGs) and the SIRT3-related DEGs. (A, B) Top 15 enriched biological processes of the SIRT3-related DEGs and the AD-related DEGs, respectively, ranked by adjusted P-value. (C, D) Top 15 enriched cellular components of the SIRT3- and AD-related DEGs, respectively. (E, F) Top 15 enriched molecular functions of the SIRT3- and AD-related DEGs, respectively. The color of the box represents the adjusted P-value of the entities, and the X axis represents the gene number involved in the entity.

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Medical Science Monitor Basic Research eISSN: 2325-4416
Medical Science Monitor Basic Research eISSN: 2325-4416